The nerve impulse is characterised by a great influx of sodium ions through channels in the neuron's cell membrane followed by an efflux of potassium ions through other channels. The neuron is unable to fire again for a short time (known as the refractory period), which is mediated by another potassium channel. The flow through these ion channels is governed by a "gate" which is opened by either a voltage change or a chemical messenger known as a ligand (such as a neurotransmitter). These channels are another target for anticonvulsant drugs.[7]
Eating salads can be helpful when trying to lose weight. A salad consisting of a ton of fresh vegetables and a few of your favourite fixings on top (bacon, cheese, dried cranberries, fresh fruit, cold cuts, chicken, or nuts) could be your favourite meal of the day. Top it with your favourite low-fat or fat-free dressing, and you have a fabulous low-fat, nutrient dense meal.
2. Actually work. Going through the motions won't help you lose weight — even if you half-ass it for 45 minutes. "From a scientific perspective, it's the intensity of exercise that raises the metabolism," says Jackowski. Instead of worrying about your heart rate, stick with this rule of thumb: If you don't feel winded and you have the capacity to step it up, you should be moving faster. So long as you tax you system, you'll benefit just as much as someone who's more fit and running faster than you on next treadmill.
As compared to other weight loss methods, swimming is proven to be more efficient in losing total body weight. A high Bodyweight largely depends on fat stores which respond very well to high intensity workouts. However, these rigorous workouts are easily accomplished in the swimming pool rather than going to the gym, jogging or even using a treadmill.
This was a great read. I aim to restrict carbs always because I believe most are why the American population is obese. I would very much like to hear more about carb restriction excluding the discussion on processed meats and processed high salt content foods because I consume neither. I also don’t consume dairy or eggs. So can you provide some substance.
If you want to be smarter in the kitchen and make better choices about the food you eat, then start with conditioning your mind. Pilates is a helpful exercise you can include in your daily routine to help you connect your mind and body. Once you manage to reach this connection, you can be more intuitive and better equipped when it comes to mealtimes.

Vegan ketogenic diet or vegetarian diet: Yes, both are possible. Instead of animal products, plenty of low-carb, nutrient-dense vegan and/or vegetarian foods are included. Nuts, seeds, low-carb fruits and veggies, leafy greens, healthy fats and fermented foods are all excellent choices on a plant-based keto diet. There’s also a similar plan called ketotarian, which combines keto with vegetarian, vegan and/or pescatarian diets for supposedly greater health benefits.
Riding a bike uses all of the largest muscles in your body: your quads, your hamstrings, your hip muscles, and your glutes. Using large muscles burns a lot of calories. An average calorie burn per hour on a bike is around 400 to 600 calories, depending on your size and how hard you pedal. So if you can ride a bike for an hour a day, you can burn up around 4,000 calories per week. This is enough to burn off a pound of fat, even without changing your diet (although it’s essential to adopt a healthier eating plan too). And because cycling is fun, you can keep doing it for long periods of time.

Vegetables and lean protein like chicken or fish should be a staple of any good cyclist's diet. Rather than loading up on nutritional supplements, try getting most of your vitamins and protein from food. The absorption rate is better, and by giving your body what it needs through the food you eat will make you feel a lot better too. And if your body feels good, you'll ride longer, which will help you burn more calories. It may also help with the junk food cravings.
10. Vary your workouts. If you do the same exact workout every day, your body will get used to it. While it might stoke your ego to perfect specific moves that used to challenge you, this mastery comes at a price: it makes everything easier, so you burn fewer calories. Instead, perform familiar exercises in a different order, try new moves with equipment you're used to, or incorporate a new fitness prop into your routine.

A lateral trainer is similar to an elliptical machine, but you move your legs side to side instead of forward and back. Since cardio machines commonly promote a forward-and-backward motion, shaking up your workout with a sideways motion amps up intensity, so you end up torching extra calories. Plus, you’ll likely target and strengthen muscles in a new way: “Lateral movement, such as what you get with lateral trainers, can really ‘wake up’ the glutes,” says Kups. (Psst: You’d be surprised at what actually counts as cardio.)
Although you'll be cutting way back on carbohydrates and sugar, some fruits are still okay to eat on the keto diet (though you'll still want to be mindful about quantity in order to remain in ketosis). The fruits that make the cut contain far fewer carbs than their off-limits cousins such as apples, pears, bananas, pineapples, papayas, grapes, and fruit juices in general.
When you eat less than 50 grams of carbs a day, your body eventually runs out of fuel (blood sugar) it can use quickly. This typically takes 3 to 4 days. Then you’ll start to break down protein and fat for energy, which can make you lose weight. This is called ketosis. It's important to note that the ketogenic diet is a short term diet that's focussed on weight loss rather than the pursuit of health benefits. 
^ Jump up to: a b c d e f g h i j k l m n o p q r s Kossoff EH, Zupec-Kania BA, Amark PE, Ballaban-Gil KR, Bergqvist AG, Blackford R, et al. Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group. Epilepsia. 2009 Feb;50(2):304–17. doi:10.1111/j.1528-1167.2008.01765.x. PMID 18823325
Pilates is a workout that's focused on elongating, chiseling, and sculpting muscles. So it’s not usually the first thing that springs to mind when it comes to weight loss. But you should rethink this, says celebrity Pilates instructor Andrea Speir whose clients include the newly slimmed down Jonah Hill. "The more muscle strength you have, the more calories you burn,” she says.
3. You'll need to really push yourself in every workout you do. It's kind of a big deal that you bring your A-game to each and every workout. "I'd rather see you do balls-to-the-wall workouts three times a week than see you give 50 percent for five days," says Rilinger. "Decide when you walk through that door you are going to give it 100 percent the entire time, and check in throughout your workout with one simple question: Can I give more?"
How long one needs to swim to lose weight totally depends upon their body weight, swimming stroke they use and speed at which they swim. According to Centre for Disease Control and Prevention one should do at least two hours and 30 minutes of swimming every week. Not only losing weight but swimming can also help you maintain your weight once you have lost the required amount. 3,500 calories are equal to a half kilo of weight. So, you need to burn 3,500 calories more apart from what you are taking in, to lose that half kilo.
The modified Atkins diet reduces seizure frequency by more than 50% in 43% of patients who try it and by more than 90% in 27% of patients.[18] Few adverse effects have been reported, though cholesterol is increased and the diet has not been studied long term.[48] Although based on a smaller data set (126 adults and children from 11 studies over five centres), these results from 2009 compare favourably with the traditional ketogenic diet.[18]
People from all age groups can use swimming as a workout. Nevertheless, it is the most fun activity during summer times. Swimming assists to improve heart and lung health, makings it an exceptional cardio workout. At the same time, it helps to improve strength and construct lean muscles. With routine swimming workouts, it is possible to get distinct abdominal muscles.
• Pancreatic insufficiency — Pancreatic insufficiency is a condition where your pancreas does not produce enough enzymes to help break down and absorb nutrients in your digestive tract. If you have an enzyme deficiency, I suggest having it treated first before embarking on a ketogenic diet, because your digestive system will have a hard time absorbing dietary fats.
This first is using a power meter. One of the key bits of data a power meter produces is the amount of work done in a ride which is expressed in kilojoules. Kilojoules convert to calories at a rate of 4.186 kilojoules per calorie. However, because we are fairly inefficient at converting our food energy into pedal power, losing about 75-80% to heat production, the actual ratio is approximately 1:1. There is some variation from rider to rider due to differing levels of efficiency but, in general, the accuracy for calorie burn calculated from power meter data is within 5%.
According to the American College of Sports Medicine’s Guidelines for Exercise Prescription, the recommendation for sustained weight-loss is 60-90 minutes of daily moderate to vigorous physical activity/exercise. At first, 60-90 minutes of exercise seems like a lot. You should start out committing to do about 30 minutes each day and gradually increase up to the recommendation. Remember, your exercise does not have to be 60 minutes all at once. It is fine to do shorter bouts of exercise. For example, you could do 30 minutes two to three times each day to equal the recommended 60-90 minutes total.

Ski machines have been around forever and it makes sense why: they rank high when it comes to zapping calories because they recruit so many large muscle groups. What’s trending these days, though, is the SkiErg machine, found in many CrossFit locations. This machine simulates cross-country skiing and is quite similar to a rowing machine, but with a vertical orientation. The goal is to pull both the machine’s cables downward at the same time, similar to how you’d use ski poles. Works the legs, arms and core. If a strong core is your goal, these ab exercises are even better than sit-ups.
Now here's a quick 10-minute total-body dumbbell workout and another 10-minute living room dumbbell workout to get you started. Here's a 20-minute strength workout for when you have a bit more time. Here's some info about how to superset at the gym. And if you're going to use kettlebells and barbells in your strength workout routine, be sure to work with a personal trainer to make sure you're using proper form. You've got this!
If you live in a challenging climate (e.g. almost anywhere in Canada!), remember that you do not have to cycle outdoors to lose weight. In the winter, spin classes could work really well for you, especially if you value having someone else to encourage and guide you. Although bear in mind that these can be quite fast-paced, so they will be a bit much for a beginner. I actually tried one back in the day when I was just starting out in cycling, and had to leave the class, red-faced and exhausted, half-way through. I was too embarrassed to ever go back – which, in retrospect, was stupid of me. Everyone has to start somewhere!
There's a reason CrossFit has become such a booming part of the workout industry—it works, so long as you don't overdo it. Workouts are varied—you may be doing anything from kettlebell swings to rope climbs and box jumps to front squats—and the routines are designed to be short and intense. The most important thing to find when looking for the box (CrossFit slang for "gym") that fits you best: a well-informed coach who can explain and modify the moves, and make sure that you don't push yourself to the point of injury. Here are a few things to keep in mind before every WOD, and here are 11 of the best CrossFit gyms in America.
Bye bye muffin top! Abdominals, a set collectively known as the core includes the many interconnected muscles that run up the back and stretch down to the butt and the front and inner thighs - not just the fat that blooms over the top of your skinny jeans. Here are weight loss exercises that will keep the love handles away:Crunches - Lie on your back with your knees bent, and your hands behind your head. Lift your shoulders off the floor and curl your legs towards your ribcage; simultaneously. Slowly, return to starting position.
If your biggest excuse for skipping a workout is being crunched for time, Tabata is your dream come true. It's designed to be four minutes of high-intensity interval training that consists of 20 seconds of all-out effort, followed by 10 seconds of rest, repeated eight times, explains Shanon Squires, an exercise physiologist and human performance lab coordinator at Colorado University Anschutz Health and Wellness Center. And you can use this protocol with any number of different exercises. You'll spike your metabolism and heart rate in four minutes, but Squires warns against making this time frame a habit if you're trying to lose weight. "Your body will quickly adapt to that interval, and you'll need to increase the volume or intensity to continue getting a benefit from it," he says. To do that, Rosante suggests extending your session to 20 minutes and following the same format. Simply pick four exercises—think jump rope, squats, mountain climbers, and squat jumps—then do each for 20 seconds as hard and fast as you can (while maintaining proper form, of course), then recovering for 10 seconds and 10 seconds only. Repeat for eight rounds on that one move (so, four minutes of work) before resting for one minute and moving on to the next exercise.
I’m following the ketogenic diet and I find it very easy, pleasant and varied. I can even say that my diet today is more varied than the previous one. I do not intend to leave this diet and I cannot really see why. My initial focus was not to lose weight, I’ve always been lean, but to feel better, well disposed. And I got it! I am very pleased, I have read a lot about it (including scientific literature) and I have influenced other people who need to lose weight or improve some aspects of their health. But from the beginning I went on my own way, without the help of a nutritionist because I did not want to suffer the influence of others’ ideas.

The CDC states that a 154-pound person burns around 510 calories by swimming laps for an hour. If you don't change your diet, you'll need to swim laps for about seven hours to lose one pound. The more you weigh, the more calories you'll burn. If you weigh 200 pounds, you'll burn around 637 calories by swimming laps for a hour while a 240-pound person would burn around 763 calories during an hour of swimming laps. Because swimming uses virtually all of the body's muscles, it can erase just as much body fat as land-based exercises. In a University of Utah study comparing exercise in water to walking on land, overweight women who swim four times a week for 40 minutes slim down just as much as women who walk the same amount of time at the same intensity level.
If you’re new or just still learning the ropes for the keto diet food list, your biggest questions probably revolve around figuring out just what high-fat low-carb foods you can eat on such a low-carb, ketogenic diet. Overall, remember that the bulk of calories on the keto diet are from foods that are high in natural fats along with a moderate amount of foods with protein. Those that are severely restricted are all foods that provide lots of carbs, even kinds that are normally thought of as “healthy,” like whole grains, for example.

If you cycle for half an hour five days per week, you can expect to burn 1,500 calories if you weigh 125 pounds and cycle at 15 miles per hour. If you can't cycle this quickly, you'll burn 1,200 calories a week cycling at 12 miles per hour. You might have to build steadily to this activity level, and cutting calories from your diet can help you spend less time cycling each week. If you feel dizzy or otherwise exhausted, decrease your activity level, and always talk to your doctor before you begin regularly cycling.
Net carbs is simply total carbs minus fiber and non-digestible sugar alcohols, like erythritol. (This doesn’t apply to high glycemic sugar alcohols, like maltitol.) We don’t have to count fiber and certain sugar alcohols in net carbs, because they either don’t get broken down by our bodies, are not absorbed, or are absorbed but not metabolized. (Read more about sugar alcohols here.)
Hi, I’m still a bit skeptical, I have seen some of my friends do the keto diet, and have had good results. Though I am still not sure about the idea of the fats being eaten. They say they eat meat with the fat and must do so, is this correct? Also isn’t this not good for the body especially for the kidneys? Second, can a diabetic do this diet? There are many questions running through my head.
When you eat less than 50 grams of carbs a day, your body eventually runs out of fuel (blood sugar) it can use quickly. This typically takes 3 to 4 days. Then you’ll start to break down protein and fat for energy, which can make you lose weight. This is called ketosis. It's important to note that the ketogenic diet is a short term diet that's focussed on weight loss rather than the pursuit of health benefits. 
People use a ketogenic diet most often to lose weight, but it can help manage certain medical conditions, like epilepsy, too. It also may help people with heart disease, certain brain diseases, and even acne, but there needs to be more research in those areas. Talk with your doctor first to find out if it’s safe for you to try a ketogenic diet, especially if you have type 1 diabetes.
A popular keto supplement are exogenous ketones (popularly called “keto diet pills”) that may help you achieve results earlier as well as remain in that state. (Don’t confuse exogenous ketones with raspberry ketones, as the latter don’t raise ketone levels in the body or mimic endogenous ketones, so you wouldn’t use raspberry ketones in your regimen.)
Losing fat and taking your body fat percent down is not as easy task. You’re going to need a great support team to help you stay on track. Make sure to get enough quality sleep per night to ensure you can recovery well in between workouts – shoot for 7-9 hours per night. Drink plenty of water spaced throughout the day and prepare healthy snacks just incase you’re out and get hungry. Remember, diet plays more of a role in fat loss than high intensity workouts. I’ll end by rephrasing a quote I read from fitness great Adam Bornstein: “Eat for the body you want, not for the body you currently have.”
This video IS challenging but totally doable! I would consider myself intermediate with Pilates and therefore I did have to break the reps a couple times to take a few second break with a few of the moves, but then could get right back into it. It is a good mixture of cardio and Pilates. I wear a size 8 / 10 and my HRM monitor told me I burned 300 cals in an hour (not counting BMR, so in reality closer to 200 cals). She is not annoying like some other Pilates instructors and the video flows really well with the included warm up and cool down. If you are wondering whether you should buy it, do it! :)
Disclaimer: if the recommendations above are not working for you, I suggest working with a nutritionist: one that can look at your training plan, use metabolic laboratory data (FAT MAX) plus your powermeter data (kJ’s = calories) AND design a meal plan for long term sustainability.  Because after all, we are talking about lifestyle changes, not diets.  Above all, congratulations on the commitment you made to your health and to your power to weight ratio!  Chris Froome here you come.
We are brazilian, living in Brazil. My daughter, Isabel, 21y. o., born in 1996, has syndrome of deficiency of Glut1. She was diagnosed around her first year of life. At that time her baby bottle, her begining diet meal, was 50ml water plus 50ml oil plus vitamin. Since then, which means, for 20 years, she is under this diet. For almost 18 years under 4:1 proportion. At this right moment 3:1. The only problem she had since started the diet were kidney stones in 2002. Nothing else. Grateful to the diet she doesn’t take any kind of medicine to avoid seizures. Her health is perfect, no colesterol at all. We are at your will for any issues related to her health.
Carbohydrate facts: Simple = bad, complex = good? Carbohydrates provide energy for the body, but the health benefits they offer depend on the type of carbs we consume. Complex carbs, found in brown rice, for example, contain more nutrients than simple carbs, such as white rice. Refined carbs, such as sugary drinks, are best avoided, as their nutritional value is low. Read now
Because it lacks carbohydrates, a ketogenic diet is rich in proteins and fats. It typically includes plenty of meats, eggs, processed meats, sausages, cheeses, fish, nuts, butter, oils, seeds, and fibrous vegetables. Because it is so restrictive, it is really hard to follow over the long run. Carbohydrates normally account for at least 50% of the typical American diet. One of the main criticisms of this diet is that many people tend to eat too much protein and poor-quality fats from processed foods, with very few fruits and vegetables. Patients with kidney disease need to be cautious because this diet could worsen their condition. Additionally, some patients may feel a little tired in the beginning, while some may have bad breath, nausea, vomiting, constipation, and sleep problems.
^ Ketogenic "eggnog" is used during induction and is a drink with the required ketogenic ratio. For example, a 4:1 ratio eggnog would contain 60 g of 36% heavy whipping cream, 25 g pasteurised raw egg, saccharin and vanilla flavour. This contains 245 kcal (1,025 kJ), 4 g protein, 2 g carbohydrate and 24 g fat (24:6 = 4:1).[17] The eggnog may also be cooked to make a custard, or frozen to make ice cream.[37]
This was my 1st time trying pilates and I've never done yoga. I am not a flexible person and have problems with chronic joint pain. The DVD was great, I did work up a sweat and burned close to 400 calories without the impact of other workouts. I admit that I could not do each move in its fullness, but I did try. There were some moves that exacerbated my joint pain, due to the stretching, and I was sore afterwards. I am confident that the more I do this workout, the bettter my body will feel. I do feel it was a good workout. The DVD is very easy to follow.

I believe (as well as the numerous experts I have interviewed) that over 90 percent of cancer cases are either preventable or treatable. The key here is to view cancer as a metabolic dysfunction, allowing you to gain control over this dreadful disease. Simply put, the right foods and strategies may help suppress cancer growth while simultaneously pushing it into remission.
Diets require discipline, and it is not always easy for people to follow them without indulging in a "cheat day." One day may not make a big difference in the long-term, but a recent study from the University of British Columbia in Okanagan, Canada (UBCO), found that when it comes to the keto diet, a single dose of carbohydrates may have dangerous side effects.
On a ketogenic diet, you’re generally eating a diet that’s high in fat (roughly 70 percent of your total calories come from fat), moderate in protein (about 20 percent of your calories), and low in carbohydrate (about 5 percent of calories). By limiting carbohydrates (to usually less than 45 grams for the average person), your body lacks the glucose (from carbs) that it normally uses for energy, so it eventually switches over to burning fat as its primary fuel source instead; through a metabolic process called ketosis, the liver converts the fat into fragments of fatty acids called ketones, which power the brain and other organs and tissues.
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Different from a standard treadmill, a curved, non-motorized one only moves when you move, adjusting its speed in real time based on your pace and rhythm. “Because the treadmill is self-powered, you must use more force while running,” says Kups. “The ability to create more force means more calories needed.” Additional benefits: The curved design provides less impact on joints than outdoor running and is especially effective for working glutes and hamstrings.
These affect your brain and spine, as well as the nerves that link them together. Epilepsy is one, but others may be helped by a ketogenic diet as well, including Alzheimer’s disease, Parkinson’s disease, and sleep disorders. Scientists aren’t sure why, but it may be that the ketones your body makes when it breaks down fat for energy help protect your brain cells from damage.
Here's the thing: Working out isn't enough on its own to make weight loss happen. There's so much else that goes into weight loss and body fat loss; in fact, exercise isn't even technically necessary in many cases. If you want to lose weight—and it's totally cool if you do and totally cool if you don't—adopting healthy eating habits has got to be step numero uno. To get technical, you need to create a calorie deficit, which means using more calories in a day than you consume—and the consumption part plays a much bigger role in that than burning calories in the gym, or while carrying your groceries home, or any of the other myriad ways you put your muscles to work each day. Other lifestyle habits, like sleep and stress management, and health conditions (think thyroid issues, to name just one of many) also affect your weight. Point is, weight loss is a complicated and extremely personal journey that doesn't look or work the exact same way from one person to the next.

First, I want to thank you for all of your dedication and work in providing this site. The difficulty of maintaining a healthy weight is a big problem for so many people. My personal question & issue in staying on Keto is my craving for fresh fruit. This a.m I had a large fresh peach along with my “Bullet Proof” coffee. Have I now sabotaged today’s Keto eating?
Losing fat and taking your body fat percent down is not as easy task. You’re going to need a great support team to help you stay on track. Make sure to get enough quality sleep per night to ensure you can recovery well in between workouts – shoot for 7-9 hours per night. Drink plenty of water spaced throughout the day and prepare healthy snacks just incase you’re out and get hungry. Remember, diet plays more of a role in fat loss than high intensity workouts. I’ll end by rephrasing a quote I read from fitness great Adam Bornstein: “Eat for the body you want, not for the body you currently have.”

Keto diets, like most low carb diets, work through the elimination of glucose. Because most folks live on a high carb diet, our bodies normally run on glucose (or sugar) for energy. We cannot make glucose and only have about 24 hours’ worth stored in our muscle tissue and liver. Once glucose is no longer available from food sources, we begin to burn stored fat instead, or fat from our food.
There’s a reason the jump rope is a mainstay in a boxer’s training regimen: it’s cheap, easy to do, increases foot speed, and burns a ton of calories. Think of your favorite boxers, wrestlers, and fighters—they all jump rope. “Jumping rope not only enhances your footwork, shoulder strength, and coordination, but also simulates sprinting, allowing you to burn as much as 500 calories in just 30 minutes,” says Ben Boudro, C.S.C.S., owner of Xceleration Fitness in Auburn Hills, MI..

Most gyms have stationary bikes, but the best ones for revving up weight loss are often found in the group exercise studio – whether you ride them as part of a class or cycle solo. “Indoor bikes for group cycling tend to fit a rider differently than a stationary bike,” says Krista Popowych, a Vancouver, B.C.-based fitness expert and Master Trainer for Keiser, a company that creates exercise equipment, including bikes and education for group cycling.

Experts recommend setting a timer on the computer to remind you to move every hour, but what's helped me is the Fitbit One ($235, amazon.com). I keep this activity tracker clipped to my bra 24/7, and I won't go to bed until I've logged 10,000 steps a day. To accomplish that, I heed some of those recommendations we've all heard a million times ("Take the stairs instead of the elevator," "Park far away from the mall"). I even jog in place while brushing my teeth and watching TV. At first my husband and son laughed their skinny little butts off at me, but now seeing me hopping around the living room strikes them as normal. Walks are part of my family's evening routine, and "How many steps do you have now?" has become the new "Are we there yet?" I've even given Fitbits to friends and family as gifts so we can see who takes the most steps. Move-more mission: accomplished.
I'm a lot like the lab rats-and humans-who turn to comfort food and pack on pounds when they're under duress. "The stress hormone cortisol triggers the fight-or-flight response, which is an appetite stimulant," Dr. Smith says. "In addition, it steps up the production of a certain brain chemical, neuropeptide Y, which increases cravings for carbohydrates." So there's actual science to support why you want to eat all the bread when you're super-stressed.
Three times a week, do the exercises here back-to-back without resting. Warm up by holding plank pose for two minutes, then do up to three circuits (beginners, start with one circuit and build up). Use a lighter kettlebell -- like four pounds -- until you get the hang of the moves, then go heavier; always choose a weight that you can control, though. No bell? Use a five- to eight-pound dumbbell instead.
Riding a bike uses all of the largest muscles in your body: your quads, your hamstrings, your hip muscles, and your glutes. Using large muscles burns a lot of calories. An average calorie burn per hour on a bike is around 400 to 600 calories, depending on your size and how hard you pedal. So if you can ride a bike for an hour a day, you can burn up around 4,000 calories per week. This is enough to burn off a pound of fat, even without changing your diet (although it’s essential to adopt a healthier eating plan too). And because cycling is fun, you can keep doing it for long periods of time.
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