18. Forget about the scale. While you might think you want to lose "weight," what you really want to lose is fat. (It takes up much more space as muscle, so it's is the real culprit when your clothes feel tight.) But oftentimes, the fat you lose weighs less than the muscle you build. So it's entirely possible to slim down without shedding actual pounds. Don't let that discourage you from sticking with your new fitness routine. If your skinniest jeans fit better than they did before you began working out, you're right on track — regardless of the number on the scale.
Fanatic? Someone with T2D, a disease usually claimed to be progressive and a never ending stream of problems and medications, was REVERSED. That’s something to shout from the rooftops. The drop in medication use alone, but the big pharma companies would prefer that people’s stories of reversing (well, putting it into remission) T2D get called fanatical instead of insightful.
The nerve impulse is characterised by a great influx of sodium ions through channels in the neuron's cell membrane followed by an efflux of potassium ions through other channels. The neuron is unable to fire again for a short time (known as the refractory period), which is mediated by another potassium channel. The flow through these ion channels is governed by a "gate" which is opened by either a voltage change or a chemical messenger known as a ligand (such as a neurotransmitter). These channels are another target for anticonvulsant drugs.
Pilates helps you burn calories, but not as many as a vigorous run or indoor cycling class. In 50 minutes of Pilates, a 150-pound woman can expect to burn between 210 and 360 calories. Exactly how many depends on the intensity of the class — advanced practitioners are usually performing moves that require more energy and muscular work, so they burn more calories.
It’s not always about how much you eat, but the nutritional balance of carbohydrates, fats, and protein in what you’re eating. Endurance athletes need extra carbs to fuel their rides, fat to feel satiated, and protein to repair your muscles post-workout. It usually isn’t necessary to make radical adjustments to achieve this balance—small changes work best. For instance, don’t eat a whole bowl of chili with meat. Instead, fill half the bowl with brown rice, then ladle a small amount of chili on top. You can also try substituting fat-free yogurt for sour cream and fruit for sweets.