Not intended for use by persons under age 18. Do not exceed recommended dose. Do not take for more than eight (8) consecutive weeks. Do not use if you are pregnant or nursing. Discontinue use two weeks prior to surgery or if upset stomach occurs. Get the consent of a licensed physician before using this product, especially if you are taking medication, have a medical condition, or thinking about becoming pregnant. Do not take this product close to bedtime. Keep this product and all supplements out of the reach of children., The recommended serving of this product contains approximately as much caffeine as two cups of coffee. Do not consume caffeine, or combine with synephrine, including but not limited to coffee, tea, soda and other dietary supplements or medications containing phenylephrine or caffeine. Too much caffeine may cause nervousness, irritability, sleeplessness, and occasionally rapid heartbeat. Discontinue use if you experience dizziness, severe headache, rapid heartbeat or shortness of breath.
Additionally, they remarked that “concerns about adverse metabolic effects of the Atkins diet were not substantiated within the 12-month study period.”  They acknowledged that more research needs to be done on the long-term effects on cardiovascular and metabolic health especially on men. However, their study supports the idea that a low-carbohydrate diet can help you lower body mass and body fat better than higher-carbohydrate alternatives.
The most important part of the ketogenic diet is consistency. Approach this diet (or any other diet that you try) with the mindset that you will make it into a long-term sustainable lifestyle. When you hit a plateau, don’t give up — we all hit plateaus eventually. Take it as an opportunity to recalculate your calorie needs, adjust your goals, and implement new strategies.
Fortunately, Drs. Kevin Hall and Juen Guo had the same burning question. In 2017, they analyzed the data and published a meta-analysis of controlled feeding studies that compared diets of equal calorie and protein content with variations in carbohydrate and fat content.  By filtering out the diet data in this way, the researchers could finally find out whether restricting carbs or limiting calories is more important when it comes to weight loss.
A ketogenic diet may be an option for some people who have had difficulty losing weight with other methods. The exact ratio of fat, carbohydrate, and protein that is needed to achieve health benefits will vary among individuals due to their genetic makeup and body composition. Therefore, if one chooses to start a ketogenic diet, it is recommended to consult with one’s physician and a dietitian to closely monitor any biochemical changes after starting the regimen, and to create a meal plan that is tailored to one’s existing health conditions and to prevent nutritional deficiencies or other health complications. A dietitian may also provide guidance on reintroducing carbohydrates once weight loss is achieved.
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Complex high fat foods such as extra virgin olive oil, when eaten with a wide variety of other healthy polyphenol-dense foods, provide the basis for a rich and diverse community of gut microbes. This diversity is increasingly being shown to be important for our health. The original PREDIMED study didn’t measure gut microbes directly (although subsequent research is doing so) but the striking benefits of the Mediterranean diet and particularly extra virgin olive oil are that they are superb gut microbe fertilisers and improve gut health.
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SOURCES: Environmental Nutrition, June 2003; May 2004; February 2005. The Journal of Pediatrics, July 1995. Journal of the American Dietetic Association, February 1997. Journal of the American Dietetic Association, July 1997. Journal of the American Medical Association, 2004; 292. Food Chemistry, May 2004, vol 85; issue 3. American Journal of Clinical Nutrition January 2005. FDA News, Nov. 1, 2004. The Olive Oil Source web site.