Because some cancer cells are inefficient in processing ketone bodies for energy, the ketogenic diet has also been suggested as a treatment for cancer. A 2018 review looked at the evidence from preclinical and clinical studies of ketogenic diets in cancer therapy. The clinical studies in humans are typically very small, with some providing weak evidence for anti-tumour effect, particularly for glioblastoma, but in other cancers and studies, no anti-tumour effect was seen. Taken together, results from preclinical studies, albeit sometimes contradictory, tend to support an anti-tumor effect rather than a pro-tumor effect of the KD for most solid cancers.
The Modified Atkins diet and modified ketogenic diet (sometimes called 'modified ketogenic therapy') use a high proportion of fats and a strict control of carbohydrates. These are often considered more flexible than the classical or MCT ketogenic diets, as more protein can be eaten, and approximate portion sizes may be used in place of weighed recipes.
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The Roux-en-Y Gastric Bypass is considered the gold standard for weight-loss surgery. Studies have shown an excess weight loss of 60 to 80 percent. This means that if you are 100 pounds overweight, we would anticipate you losing 60-80 pounds after weight loss surgery. Most patients will maintain a 50 percent excess weight loss when they are 10 years out from surgery.
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In open bariatric surgery, surgeons make a single, large cut in the abdomen. More often, surgeons now use laparoscopic surgery, in which they make several small cuts and insert thin surgical tools through the cuts. Surgeons also insert a small scope attached to a camera that projects images onto a video monitor. Laparoscopic surgery has fewer risks than open surgery and may cause less pain and scarring than open surgery. Laparoscopic surgery also may lead to a faster recovery.
Phentermine-topiramate is a combination of an anticonvulsant (topiramate) and a weight-loss drug (phentermine). Phentermine has the potential to be abused because of its amphetamine-like effects. Other possible side effects include an increase in heart rate and blood pressure, insomnia, constipation and nervousness. Topiramate increases the risk of birth defects.